Wednesday, July 22

08:30 - 09:10 am

Opening Plenary Session

08:30 Introduction & welcome from Protein Society President
James Bowie
, University of California. Los Angeles, CA, United States.
08:35 Presentation of the 2015 Hans Neurath Award* to Marina Rodnina
08:40 Marina Rodnina, Max Planck Institute for Biophysical Chemistry. Göttingen, Germany.
The Ribosome in Action: Following Protein Synthesis in Real Time.
* sponsored by the Hans Neurath Foundation

09:10 - 09:40 am

Morning Meet-Up Coffee Break

09:40 - 11:30 am

Enzyme & Pathway Engineering
CONCURRENT MORNING SYMPOSIA 1
Room 6 (room 5 - overflow)

09:40 Intro from Chair: F. Xavier Gomis-Rüth, IBMB-CSIC. Barcelona, Spain.

09:45 Eric Brustad, University of North Carolina. Chapel Hill, NC, United States.
New recipes for biocatalysis: Expanding the cytochrome P450 reaction landscape for non-natural chemistry.

10:15 Chaitan Khosla, Stanford University. Stanford, CA, United States. 
Assembly Line Biosynthesis of Polyketide Antibiotics.

Young Investigator Speaker
10:45 Malgorzata Nocula-Lugowska, University of Chicago, IL, United States.
Conformation-specific Antibodies as Enhancers and Inhibitors of Phosphatase Activity of DEP 1.

11:00 Lynne Regan, Yale University. New Haven, CT, United States.
Novel strategies for pathway engineering in vivo
.

Proteomics (PTMs, PPIs)
CONCURRENT MORNING SYMPOSIA 2
Auditorium

09:40
Intro from Chair: Francesc Xavier Aviles,  Universitat Autònoma de Barcelona. Barcelona, Spain.

09:45 Ruedi Aebersold, Eidgenössische Technische Hochschule Zürich. Zürich, Switzerland.
Chemical Cross-linking/Mass Spectrometry and the Structural Biology Toolbox.

10:15 Andrej Sali, University of California. San Francisco, CA, United States.
Integrative Structural Biology.

Young Investigator Speaker
10:45 Olivier Julien, University of California. San Francisco, CA, United States.
Global Kinetic Analysis of Caspase-2 and Caspase-6 Proteolysis in Cellular Extract Reveals Target Specificity Beyond the Substrate Primary Sequence.

11:00 Brenda Andrews, University of Toronto. Toronto, ON, Canada.
Yeast Proteome Dynamics from Single Cell Imaging and Automated Analysis.

11:30 am - 01:30 pm

Lunch
Poster Displays and Exhibits Open – Exhibit Hall

Noon - 01:00 pm Workshop: Career Panel
Room 3

Noon - 01:00 pm Undergraduate Student Research Session
Room 8

Exhibitor Lunch Workshop


Noon - 01:00 pm
Enabling high resolution protein interaction analysis with PEAQ-ITC.
Presented by Ms. Natalia Markova

01:30 - 04:30 pm

 

 

 

 

 




 

Cell Engineering
CONCURRENT AFTERNOON SYMPOSIA 1
Room 6 (room 5 - overflow)

01:30 Intro from Chair: Bryan Berger, Lehigh University. Bethlehem, PA, United States. 

01:35
Miki Ebisuya, RIKEN Quantitative Biology Center. Kobe, Japan.
Reconstitution of an Intercellular Symmetry Breaking Mechanism Driven by Delta-Notch Signaling.

Young Investigator Speaker
02:05
Shiksha Mantri, ETH Zurich. 
Bottom-up construction of a synthetic carboxysome.

02:20
Brian Kuhlman, University of North Carolina. Chapel Hill, NC, United States. 
Engineering Light-Activatable Proteins for Controlling Cell Signaling Pathways.

02:50
25-min Coffee Break

03:15 Stephen Michnick, University of Montreal. Montreal, QC, Canada.
Phasing and Dephasing Cell Morphogenesis.

Young Investigator Speaker
03:45 Tayler Korman, University of California. Los Angeles, CA, United States.
Development and Use of a Molecular Purge Valve to Maintain Reduction/Oxidation Balance in Synthetic Biochemistry Systems.

04:00 Zev Gartner, University of California. San Francisco, CA, United States.
Engineering Cell-cell Interactions.

Protein Engineering
CONCURRENT AFTERNOON SYMPOSIA 2
Auditorium

01:30 Intro from Chair: Beatriz Ibarra-Molero,  Universidad de Granada. Granada, Spain. 

01:35 David Liu,  Harvard University/HHMI. Cambridge, MA, United States. 
Engineering the Specificity and Delivery of Genome-Editing Proteins.

Young Investigator Speaker
02:05 Gustav Oberdorfer, University of Washington. Seattle, WA, United States.
Parametric Design of Alpha-helical Barrels and Pore-like Assemblies with Very High Thermodynamic Stabilities..

02:20 Ronald Raines, University of Wisconsin. Madison, WI, United States.
Ribonuclease A: From kcat/KM to the Clinic

02:50 25-min Coffee Break

03:15 Sierin Lim, Nanyang Technological University. Singapore, Republic of Singapore. 
Engineering Protein-Protein Interaction for Tunable Assembly and Release of Molecular Cargos from Protein Cages.

Protein Science Best Paper Speaker
03:45 Minttu Virkki, Stockholm University. Stockholm, Sweden.
Folding of Aquaporin 1: How Marginally Hydrophobic Transmembrane Helices Can Shape Membrane Protein Folding

04:00 Anthony KossiakoffUniversity of Chicago. Chicago, IL, United States.
Modifying Biological Function Using Conformational Trapping by Customized Synthetic Antibodies.

04:30 - 06:30 pm Poster Displays, Exhibits Open
05:30 pm Mix & Mingle Reception
07:00 - 08:45pm

Networking dinner. RSVP event
Cafeteria

09:00 pm - 11:00 pm Happy Hour in Honor of the 2015 Young Investigator Speakers