08:30 - 09:10 am |
Opening Plenary Session
08:30 Introduction & welcome from Protein Society President
James Bowie, University of California. Los Angeles, CA, United States.
08:35 Presentation of the 2015 Hans Neurath Award* to Marina Rodnina
08:40 Marina Rodnina, Max Planck Institute for Biophysical Chemistry. Göttingen, Germany.
The Ribosome in Action: Following Protein Synthesis in Real Time.
* sponsored by the Hans Neurath Foundation
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09:40 - 11:30 am
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Enzyme & Pathway Engineering
CONCURRENT MORNING SYMPOSIA 1
Room 6 (room 5 - overflow)
09:40 Intro from Chair: F. Xavier Gomis-Rüth, IBMB-CSIC. Barcelona, Spain.
09:45 Eric Brustad, University of North Carolina. Chapel Hill, NC, United States.
New recipes for biocatalysis: Expanding the cytochrome P450 reaction landscape for non-natural chemistry.
10:15 Chaitan Khosla, Stanford University. Stanford, CA, United States.
Assembly Line Biosynthesis of Polyketide Antibiotics.
Young Investigator Speaker
10:45 Malgorzata Nocula-Lugowska, University of Chicago, IL, United States.
Conformation-specific Antibodies as Enhancers and Inhibitors of Phosphatase Activity of DEP 1.
11:00 Lynne Regan, Yale University. New Haven, CT, United States.
Novel strategies for pathway engineering in vivo.
Proteomics (PTMs, PPIs)
CONCURRENT MORNING SYMPOSIA 2
Auditorium
09:40
Intro from Chair:
Francesc Xavier Aviles,
Universitat Autònoma de Barcelona. Barcelona, Spain.
09:45
Ruedi Aebersold,
Eidgenössische Technische Hochschule Zürich. Zürich, Switzerland.
Chemical Cross-linking/Mass Spectrometry and the Structural Biology Toolbox.
10:15 Andrej Sali, University of California. San Francisco, CA, United States.
Integrative Structural Biology.
Young Investigator Speaker
10:45 Olivier Julien, University of California. San Francisco, CA, United States.
Global Kinetic Analysis of Caspase-2 and Caspase-6 Proteolysis in Cellular Extract Reveals Target Specificity Beyond the Substrate Primary Sequence.
11:00 Brenda Andrews, University of Toronto. Toronto, ON, Canada.
Yeast Proteome Dynamics from Single Cell Imaging and Automated Analysis. |
01:30 - 04:30 pm
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Cell Engineering
CONCURRENT AFTERNOON SYMPOSIA 1
Room 6 (room 5 - overflow)
01:30 Intro from Chair: Bryan Berger, Lehigh University. Bethlehem, PA, United States.
01:35 Miki Ebisuya, RIKEN Quantitative Biology Center. Kobe, Japan.
Reconstitution of an Intercellular Symmetry Breaking Mechanism Driven by Delta-Notch Signaling.
Young Investigator Speaker
02:05 Shiksha Mantri, ETH Zurich.
Bottom-up construction of a synthetic carboxysome.
02:20 Brian Kuhlman, University of North Carolina. Chapel Hill, NC, United States.
Engineering Light-Activatable Proteins for Controlling Cell Signaling Pathways.
02:50 25-min Coffee Break
03:15 Stephen Michnick, University of Montreal. Montreal, QC, Canada.
Phasing and Dephasing Cell Morphogenesis.
Young Investigator Speaker
03:45 Tayler Korman, University of California. Los Angeles, CA, United States.
Development and Use of a Molecular Purge Valve to Maintain Reduction/Oxidation Balance in Synthetic Biochemistry Systems.
04:00 Zev Gartner, University of California. San Francisco, CA, United States.
Engineering Cell-cell Interactions.
Protein Engineering
CONCURRENT AFTERNOON SYMPOSIA 2
Auditorium
01:30 Intro from Chair: Beatriz Ibarra-Molero, Universidad de Granada. Granada, Spain.
01:35 David Liu, Harvard University/HHMI. Cambridge, MA, United States.
Engineering the Specificity and Delivery of Genome-Editing Proteins.
Young Investigator Speaker
02:05 Gustav Oberdorfer, University of Washington. Seattle, WA, United States.
Parametric Design of Alpha-helical Barrels and Pore-like Assemblies with Very High Thermodynamic Stabilities..
02:20 Ronald Raines, University of Wisconsin. Madison, WI, United States.
Ribonuclease A: From kcat/KM to the Clinic
02:50 25-min Coffee Break
03:15 Sierin Lim, Nanyang Technological University. Singapore, Republic of Singapore.
Engineering Protein-Protein Interaction for Tunable Assembly and Release of Molecular Cargos from Protein Cages.
Protein Science Best Paper Speaker
03:45 Minttu Virkki, Stockholm University. Stockholm, Sweden.
Folding of Aquaporin 1: How Marginally Hydrophobic Transmembrane Helices Can Shape Membrane Protein Folding
04:00 Anthony Kossiakoff, University of Chicago. Chicago, IL, United States.
Modifying Biological Function Using Conformational Trapping by Customized Synthetic Antibodies. |